Single-cell proteogenomics of the human cell cycle
The cell cycle is driven by precise regulation of proteins in time and space, which also causes cell-to-cell heterogeneity. To study this heterogeneity in co...
Research
Proteogenomic database creation
Each of us has thousands of variations in our genomes, alternative splicing in our transcriptomes, and post-translational modifications (PTMs) adorning our p...
Proteoform family identification, quantification, and visualization
Proteoform families I created software named Proteoform Suite that automated the identification, quantification, and visualization of proteoform families, i....
Discovered lncRNAs that differentiate aggressive and indolent prostate cancers
Distinguishing between aggressive and indolent prostate cancers is currently performed by invasive biopsies and traditional and imprecise immunohistopatholog...
Validated new techniques for hybridization capture analysis of RNA- and DNA-binding proteins
Ensembles of proteins bind RNA and DNA and have typically been profiled by immunoprecipitation (IP) methods that pull down proteins along with their nucleic ...